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A conserved arginine with non‐conserved function is a key determinant of agonist selectivity in α7 nicotinic ACh receptors
(Wiley Blackwell Publishing, Inc, 2021-04)
The α7 and α4β2* (“*” denotes possibly assembly with another subunit) nicotinic acetylcholine receptors (nAChRs) are the most abundant nAChRs in the mammalian brain. These receptors are the most targeted nAChRs in drug ...
Biochemical and MALDI-TOF mass spectrometric characterization of a novel native and recombinant cystine knot miniprotein from Solanum tuberosum subsp. andigenum cv. Churqueña
(Molecular Diversity Preservation International, 2018-03)
Cystine-knot miniproteins (CKMPs) are an intriguing group of cysteine-rich molecules that combine the characteristics of proteins and peptides. Typically, CKMPs are fewer than 50 residues in length and share a characteristic ...
Sulfur‐containing amino acids that increase renal glutathione protect the kidney against papillary necrosis induced by 2‐bromoethylamine
(1990)
Papillary necrosis was observed in the kidneys of rats, 72 h after receiving a single injection of bromoethylamine (BEA). This effect was associated with renal glutathione (GSH) depletion 1 h after the administration of ...
Discovery of a Beetroot Protease Inhibitor to Identify and Classify Plant-Derived Cystine Knot Peptides
(2020-11-25)
Plant peptide protease inhibitors are important molecules in seed storage metabolism and to fight insect pests. Commonly they contain multiple disulfide bonds and are exceptionally stable molecules. In this study, a novel ...
Electrocatalytic activity of vitamin B12 adsorbed on graphite electrode for the oxidation of cysteine and glutathione and the reduction of cystine
(1994)
We have investigated the electrocatalytic activity of vitamin B12 adsorbed on ordinary pyrolytic graphite (OPG) for the oxidation of cysteine and glutathione and for the reduction of cystine, using cyclic voltammetry and ...
Role of a cystine-based Gemini surfactant ligand in the synthesis of catalytic active silver nanoparticles
(Elsevier Science, 2019-06)
We report the synthesis in water of colloidal silver nanoparticles (AgNP) using a Gemini lipoamino acid surfactant derived from cysteine as a capping agent. The Gemini surfactant interacts with the metal surface mainly in ...
QUENCHING OF TRIPLET BENZOPHENONE BY VITAMINS E and C and BY SULFUR CONTAINING AMINO ACIDS and PEPTIDES
(1985)
Abstract— The quenching rate of triplet benzophenone in water and/or water mixtures has been determined employing vitamin C, vitamin E, cystine, cysteine, reduced and oxidized glutathione, methionine and DL‐penicillamine. ...
Effect of Roasting on the Chemical Composition and Protein Quality of Lupin Seeds (Lupinus albus cv Multolupa)
(1986)
The effect of roasting lupin seeds (Lupinus albus cv Multolupa) for 10, 20, 30, and 40 min at 80–90°C was studied. Raw lupin was shown to be markedly deficient in the S‐amino acids. These were not affected by roasting for ...
Cistinosis nefropática: caso clínico que ilustra diagnóstico molecular
(Sociedad Médica de Santiago, 2018)
Nephropatic cystinosis (NC) is a rare disease associated with pathogenic variants in the CTNS gene, with a common variant that consists of a 57kb-deletion involving CTNS. Patients with NC that are treated with cysteamine ...